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Article

von Willebrand factor propeptide to antigen ratio identifies platelet activation and reduced von Willebrand factor survival phenotype in mice.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2018

Jacobi P M, Kanaji S, Jakab D, Gehrand A L, Johnsen J M, Haberichter S L

Abstract excerpt

Essentials Reduced survival of von Willebrand factor (VWF) in plasma causes type 1C von Willebrand disease. Blood was collected from mouse strains by various methods and VWF propeptide and antigen assayed. VWF propeptide to antigen ratio identifies a reduced VWF survival phenotype in mice. This ratio validates the acceptability of murine blood samples for coagulation studies. SUMMARY: Background Reduced plasma...

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Source

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Identifiers

PMID: 29285851
DOI: 10.1111/jth.13934
PMCID: PMC5826853

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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