Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADAMTS13 assays and ADAMTS13-deficient mice.

Current opinion in hematology - 1 May 2007

Miyata Toshiyuki, Kokame Koichi, Banno Fumiaki, Shin Yongchol, Akiyama Masashi

Abstract excerpt

PURPOSE OF REVIEW: Thrombotic thrombocytopenic purpura can be induced by acquired or congenital deficiency of the plasma von Willebrand factor-cleaving protease, ADAMTS13. Measurement of ADAMTS13 activity is important for the diagnosis and treatment of microangiopathies including thrombotic throm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Metalloendopeptidases
Share to Mice
Share to Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ADAMTS13 Protein

Share to ADAMTS13 gene

Share to Genetic Predisposition to Disease

Share to Purpura, Thrombotic Thrombocytopenic

Source

Identifiers

PMID: 17414219
DOI: 10.1097/MOH.0b013e3280d3580c

Genes

ADAMTS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17414219-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADAMTS13 assays and ADAMTS13-deficient mice.PMID 17414219Read ↗

Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

Molecular basis of ADAMTS13 dysfunction in thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

[Thrombotic Thrombocytopenic Purpura --Pathophysiology and Assays of ADAMTS13 Activity].Semantic proximity Read ↗

Inherited ADAMTS13 mutations associated with Thrombotic Thrombocytopenic Purpura: a short review and update.Semantic proximity Read ↗

An update on the pathogenesis and diagnosis of thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2BSemantic proximity Read ↗

Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice.Semantic proximity Read ↗

Hereditary Thrombotic Thrombocytopenic Purpura in a 9-Month-old: Diagnosing and Managing an Ultra-rare Disorder.Semantic proximity Read ↗

An IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers.Semantic proximity Read ↗

Structural and functional correlation of ADAMTS13.Semantic proximity Read ↗

Hereditary Thrombotic Thrombocytopenic Purpura.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.