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Article

NLRP3 Controls the Development of Gastrointestinal CD11b+ Dendritic Cells in the Steady State and during Chronic Bacterial Infection

1 Dec 2017

Abstract excerpt

The gastric lamina propria is largely uncharted immunological territory. Here we describe the evolution and composition of the gastric, small intestinal, and colonic lamina propria mononuclear phagocyte system during the steady state and infection with the gastric pathogen Helicobacter pylori . We show that monocytes, CX 3 CR1 hi macrophages, and CD11b + dendritic cells are recruited to the infected stomach in a...

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PMID: 29281833
DOI: 10.1016/j.celrep.2017.12.015

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