Article
Origin of the lamina propria dendritic cell network.
Immunity - 18 Sept 2009
Bogunovic Milena, Ginhoux Florent, Helft Julie, Shang Limin, Hashimoto Daigo, Greter Melanie, Liu Kang, Jakubzick Claudia, Ingersoll Molly A, Leboeuf Marylene, Stanley E Richard, Nussenzweig Michel, Lira Sergio A, Randolph Gwendalyn J, Merad Miriam
Abstract excerpt
CX(3)CR1(+) and CD103(+) dendritic cells (DCs) in intestinal lamina propria play a key role in mucosal immunity. However, the origin and the developmental pathways that regulate their differentiation in the lamina propria remain unclear. We showed that monocytes gave rise exclusively to CD103(-)C...
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