The Cag pathogenicity island and interaction between <scp>TLR</scp>2/<scp>NOD</scp>2 and <scp>NLRP</scp>3 regulate <scp>IL</scp>‐1β production in <i>Helicobacter pylori</i> infected dendritic cells

Abstract excerpt

Helicobacter pylori colonization of the stomach affects about half of the world population and is associated with the development of gastritis, ulcers, and cancer. Polymorphisms in the IL1B gene are linked to an increased risk of H. pylori associated cancer, but the bacterial and host factors that regulate interleukin (IL)-1β production in response to H. pylori infection remain unknown. Using murine BM-derived...

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