Article
Divergent brain changes in two audiogenic rat strains: A voxel-based morphometry and diffusion tensor imaging comparison of the genetically epilepsy prone rat (GEPR-3) and the Wistar Audiogenic Rat (WAR).
Neurobiology of disease - 1 Mar 2018
Lee Yichien, Rodriguez Olga C, Albanese Chris, Santos Victor Rodrigues, Cortes de Oliveira José Antônio, Donatti Ana Luiza Ferreira, Fernandes Artur, Garcia-Cairasco Norberto, N'Gouemo Prosper, Forcelli Patrick A
Abstract excerpt
Acoustically evoked seizures (e.g., audiogenic seizures or AGS) are common in models of inherited epilepsy and occur in a variety of species including rat, mouse, and hamster. Two models that have been particularly well studied are the genetically epilepsy prone rat (GEPR-3) and the Wistar Audiogenic Rat (WAR) strains. Acute and repeated AGS, as well as comorbid conditions, displays a close phenotypic overlap in...
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