Article
Inherent Susceptibility to Acquired Epilepsy in Selectively Bred Rats Influences the Acute Response to Traumatic Brain Injury.
Journal of neurotrauma - 1 Oct 2023
Leung Wai Lam, Dill Larissa K, Perucca Piero, O'Brien Terence J, Casillas-Espinosa Pablo M, Semple Bridgette D
Abstract excerpt
Traumatic brain injury (TBI) often causes seizures associated with a neuroinflammatory response and neurodegeneration. TBI responses may be influenced by differences between individuals at a genetic level, yet this concept remains understudied. Here, we asked whether inherent differences in one's vulnerability to acquired epilepsy would determine acute physiological and neuroinflammatory responses acutely after...
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