Article
The development of transient SV40 based shuttle vectors for mutagenesis studies: problems and solutions.
Mutation research - 1 Jan 2000
Seidman M
Abstract excerpt
Shuttle-vector plasmids would appear to provide a powerful technology for studying mutagenesis in mammalian (including human) cells. Recently, as described in this and other papers in this volume, several shuttle-vector systems have been described and applied. The development of the first shuttle vectors for these purposes was hindered by two major problems. The first of these was the 'poison' sequence present in...
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