Article
Molecular analysis of mutations induced by chemical carcinogens in mammalian cells. II. The use of recombinant DNA vectors.
Annali dell'Istituto superiore di sanita - 1 Jan 1994
Basic-Zaninovic T, Palombo F, Calcagnile A S, Dogliotti E
Abstract excerpt
One approach to molecular and mechanistic studies of mutagenesis in mammalian cells is to introduce a mutational target gene into the cells as part of a shuttle vector which is capable of replication in both mammalian cells and bacteria. Following mutagenesis in the mammalian cell host, the shutt...
Topics
- Alkylating Agents
- Animals
- Antineoplastic Agents
- Base Sequence
- Carcinogens
- Cells, Cultured
- DNA, Recombinant
- Genetic Vectors
- Mammals
- Molecular Sequence Data
- Mutagens
- Mutation
