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Interferon Lambda Genetics and Biology in Regulation of Viral Control

6 Dec 2017

Abstract excerpt

Type III interferons, also known as interferon lambdas (IFNλs), are the most recent addition to the IFN family following their discovery in 2003. Initially, IFNλ was demonstrated to induce expression of interferon stimulated genes (ISGs) and exert antiviral properties in a similar manner to type I IFNs. However, while IFNλ has been described to have largely overlapping expression and function with type I IFNs, it...

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PMID: 29270173
DOI: 10.3389/fimmu.2017.01707

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