GIGI-Quick: a fast approach to impute missing genotypes in genome-wide association family data.

Abstract excerpt

Summary: Genome-wide association studies have become common over the last ten years, with a shift towards targeting rare variants, especially in pedigree-data. Despite lower costs, sequencing for rare variants still remains expensive. To have a relatively large sample with acceptable cost, imputation approaches may be used, such as GIGI for pedigree data. GIGI is an imputation method that handles large pedigrees...

Topics

• Genome-Wide Association Study
• Genotype
• Pedigree
• Software