Article
Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease
4 May 2016
Abstract excerpt
Abstract Ankylosing spondylitis (AS) is a common chronic immune-mediated arthropathy affecting primarily the spine and pelvis. The condition is strongly associated with HLA-B*27 as well as other human leukocyte antigen variants and at least 47 individual non-MHC-associated variants. However, substantial additional heritability remains as yet unexplained. To identify further genetic variants associated with the...
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