Article

Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis

2023-09-26

Abstract excerpt

<h4>Objective</h4> Multiple lines of evidence indicate that ankylosing spondylitis (AS) is a lymphocyte-driven disease. However, which lymphocyte populations are critical in AS pathogenesis is not known. In this study, we aimed to identify the key cell types mediating the genetic risk in AS using an unbiased functional genomics approach. <h4>Methods</h4> We integrated genome-wide association study (GWAS) data with...

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Literature Corpus work: 2949e39c-1b6c-52b2-bcca-666f83416da9
DOI: 10.1101/2023.09.21.23295912

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