Article

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at <i>ADCY7</i>

2016-06-11

Abstract excerpt

In order to further resolve the genetic architecture of the inflammatory bowel diseases, ulcerative colitis and Crohn’s disease, we sequenced the whole genomes of 4,280 patients at low coverage, and compared them to 3,652 previously sequenced population controls across 73.5 million variants. To increase power we imputed from these sequences into new and existing GWAS cohorts, and tested for association at ~12 mill...

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Literature Corpus work: 982c0a88-208b-582b-b06c-58b132b58e4d
DOI: 10.1101/058347

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