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Article

Characterizing the effect of supplements on the phenotype of cultured macrophages from patients with age-related macular degeneration.

Molecular vision - 1 Jan 2017

Rinsky Batya, Hagbi-Levi Shira, Elbaz-Hayoun Sarah, Grunin Michelle, Chowers Itay

Abstract excerpt

Purpose: Oral vitamin and mineral supplements reduce the risk of visual loss in age-related macular degeneration (AMD). However, the pathways that mediate this beneficial effect are poorly understood. Macrophages may exert oxidative, inflammatory, and angiogenic effects in the context of AMD. We aim to assess if oral supplements can modulate the macrophage phenotype in this disease. Methods: Monocytes were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29259394
PMCID: PMC5723149

Genes

HMOX1
SOD1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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