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Article

Proangiogenic characteristics of activated macrophages from patients with age-related macular degeneration.

Neurobiology of aging - 1 Mar 2017

Hagbi-Levi Shira, Grunin Michelle, Jaouni Tareq, Tiosano Liran, Rinsky Batya, Elbaz-Hayoun Sarah, Peled Amnon, Chowers Itay

Abstract excerpt

Macrophages were previously implicated in the pathogenesis of neovascular age-related macular degeneration (nvAMD). It is unclear if a specific macrophage phenotype is associated with nvAMD, and if macrophages from nvAMD patients are more pathogenic as compared with controls. To address these issues, we evaluated macrophages derived from peripheral blood monocytes of nvAMD patients and age-matched controls....

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PMID: 28039766
DOI: 10.1016/j.neurobiolaging.2016.11.018

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