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Article

Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours.

Scientific reports - 19 Dec 2017

FitzGerald Liesel M, Raspin Kelsie, Marthick James R, Field Matt A, Malley Roslyn C, Thomson Russell J, Blackburn Nicholas B, Banks Annette, Charlesworth Jac C, Donovan Shaun, Dickinson Joanne L

Abstract excerpt

The HOXB13 G84E variant is associated with risk of prostate cancer (PCa), however the role this variant plays in PCa development is unknown. This study examined 751 cases, 450 relatives and 355 controls to determine the contribution of this variant to PCa risk in Tasmania and investigated HOXB13 gene and protein expression in tumours from nine G84E heterozygote variant and 13 wild-type carriers. Quantitative PCR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29259341
DOI: 10.1038/s41598-017-18217-w
PMCID: PMC5736598

Genes

HOXB13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours.PMID 29259341Read ↗

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