Article
Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy.
The Journal of urology - 1 Mar 2013
Schroeck Florian R, Zuhlke Kimberly A, Siddiqui Javed, Siddiqui Rabia, Cooney Kathleen A, Wei John T
Abstract excerpt
PURPOSE: The G84E variant of HOXB13 was recently found to be associated with a significantly increased risk of prostate cancer in a case control study. We estimated the prevalence of this mutation in a clinical population of men at risk for prostate cancer who were scheduled to undergo prostate biopsy. MATERIALS AND METHODS: We prospectively collected clinical information and DNA samples from men who underwent...
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