Article
Associations of genetic susceptibility and healthy lifestyle with incidence of coronary heart disease and stroke in individuals with hypertension.
European journal of preventive cardiology - 15 Nov 2022
Wang Mengyao, Brage Soren, Sharp Stephen J, Luo Shan, Au Yeung Shiu Lun, Kim Youngwon
Abstract excerpt
AIMS: This study explored the associations of genetic susceptibility and adherence to a healthy lifestyle with incident coronary heart disease (CHD) and stroke in individuals with hypertension. METHODS AND RESULTS: This study included 258 531 European descendants with hypertension at baseline from UK Biobank. Genetic risk of CHD and stroke was estimated using polygenic risk scores derived from 300 and 87...
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