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Article

Prospective associations of genetic susceptibility to high blood pressure and muscle strength with incident cardiovascular disease outcomes.

Journal of hypertension - 1 Feb 2025

Wang Mengyao, Collings Paul James, Jang Haeyoon, Chen Ziyuan, Luo Shan, Au Yeung Shiu Lun, Sharp Stephen J, Brage Soren, Kim Youngwon

Abstract excerpt

BACKGROUND: This study explored the prospective associations of genetic susceptibility to high blood pressure (BP) and muscle strength with cardiovascular disease (CVD) mortality, incident coronary heart disease (CHD) and incident stroke. METHODS: This study included 349 085 white British individuals from the UK Biobank study. Genetic risk of high BP was estimated using a weighted polygenic risk score that...

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PMID: 39445587
DOI: 10.1097/HJH.0000000000003900

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