Article
Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment.
Pharmacogenetics and genomics - 1 Aug 2009
Ferris Steven, Nordberg Agneta, Soininen Hilkka, Darreh-Shori Taher, Lane Roger
Abstract excerpt
OBJECTIVE: Evaluate the effect of sex and butyrylcholinesterase (BuChE) genotype on the incidence of Alzheimer's disease (AD), cognitive and functional decline, brain volume changes, and response to rivastigmine treatment in individuals with mild cognitive impairment (MCI). METHODS: This retrospective exploratory analysis from a 3-4 year, randomized, placebo-controlled study of rivastigmine in MCI patients...
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