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Article

Selection on non-antigenic gene segments of seasonal influenza A virus and its impact on adaptive evolution

1 Jul 2017

Abstract excerpt

Most studies on seasonal influenza A/H3N2 virus adaptation have focused on the main antigenic gene, hemagglutinin. However, there is increasing evidence that the genome-wide genetic background of novel antigenic variants can influence these variants' emergence probabilities and impact their patterns of dominance in the population. This suggests that non-antigenic genes may be important in shaping the viral...

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PMID: 29250432
DOI: 10.1093/ve/vex034

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