Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging Insights into Liver X Receptor α in the Tumorigenesis and Therapeutics of Human Cancers

28 Jul 2023

Abstract excerpt

Liver X receptor α (LXRα), a member of the nuclear receptor superfamily, is identified as a protein activated by ligands that interacts with the promoters of specific genes. It regulates cholesterol, bile acid, and lipid metabolism in normal physiological processes, and it participates in the development of some related diseases. However, many studies have demonstrated that LXRα is also involved in regulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37627249
DOI: 10.3390/biom13081184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging Insights into Liver X Receptor α in the Tumorigenesis and Therapeutics of Human CancersPMID 37627249Read ↗

The emerging roles of liver X receptors and their ligands in cancerSemantic proximity Read ↗

The roles of liver X receptor α in inflammation and inflammation‐associated diseasesSemantic proximity Read ↗

Liver X receptors as potential targets for cancer therapeutics (Review)Semantic proximity Read ↗

Comprehensive profiling of liver x receptor splicing in triple negative breast cancer reveals existence of novel splice variants that are prognostic for survivalSemantic proximity Read ↗

O-GlcNAc site-mapping of liver X receptor-α and O-GlcNAc transferase.Semantic proximity Read ↗

Mechanisms and Therapeutic Advances of PXR in Metabolic Diseases and CancerSemantic proximity Read ↗

Analysis of the Expression and Prognosis for Leukocyte Immunoglobulin-Like Receptor Subfamily B in Human Liver CancerSemantic proximity Read ↗

The role of hepatocyte nuclear factor 4α (HNF4α) in tumorigenesisSemantic proximity Read ↗

RORγ is a context-specific master regulator of cholesterol biosynthesis and an emerging therapeutic target in cancer and autoimmune diseasesSemantic proximity Read ↗

Comprehensive pan-cancer analysis and experimental validation of TRAP1 as a possible medicinal targetSemantic proximity Read ↗

Targeting liver X receptors in human health: deadlock or promising trail?Semantic proximity Read ↗

Targeting liver X receptors in inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.