Article

Liver-X receptor β-selective agonist CE9A215 regulates Alzheimer’s disease- associated pathology in a 3xTg-AD mouse model

2024-11-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> In Alzheimer's disease (AD), tau pathology is more closely associated with disease progression. Therefore, the development of agents that alleviate tau pathology is essential. Liver-X receptor (LXR), a nuclear receptor with α and β subunits, has garnered interest for the prevention and treatment of neurodegenerative diseases, especially AD. Inotodiol (CE9A215) is...

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Literature Corpus work: fd5b9a63-4b95-5ef6-9afe-638e86b8fb61
DOI: 10.21203/rs.3.rs-5357448/v1

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