Article
Common variants of ROCKs and the risk of hypertension, and stroke: Two case-control studies and a follow-up study in Chinese Han population.
Biochimica et biophysica acta. Molecular basis of disease - 1 Mar 2018
Yang Song, Zhao Yanping, Tian Yuanrui, Chen Yanchun, Zhao Xianghai, Li Ying, Zhao Hailong, Chen Xiaotian, Zhu Lijun, Fang Zhengmei, Yao YingShui, Hu Zhibing, Shen Chong
Abstract excerpt
The Rho kinases (ROCKs) are recognized as a critical regulator of vascular functions in cardiovascular disorders. It is crucial to illustrate the association of ROCKs genetic variation and hypertension and/or stroke events. Herein we aimed at investigating the association of ROCK1 and ROCK2 with hypertension and stroke in Chinese Han population. Seven tagSNPs at ROCK1 and ROCK2 were genotyped in a community-based...
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