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Article

Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.

Clinical science (London, England : 1979) - 1 Jun 2014

Zee Robert Y L, Wang Qing-Mei, Chasman Daniel I, Ridker Paul M, Liao James K

Abstract excerpt

Recent animal and human studies have demonstrated the importance of the ROCK (RhoA/Rho-associated kinase) pathway in IsST (ischaemic stroke). Whether the genetic variation within ROCK-associated genes modulates the risk of IsST remains elusive. The association between 66 tSNPs [tagging SNPs (single nucleotide polymorphisms)] of three ROCK-associated genes [ROCK1, ROCK2 and ARHGEF10 (Rho...

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Share to Brain Ischemia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 24351102
DOI: 10.1042/CS20130652
PMCID: PMC4059841

Genes

ROCK1
ARHGEF10
ROCK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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