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Article

Dolutegravir reshapes the genetic diversity of HIV-1 reservoirs.

The Journal of antimicrobial chemotherapy - 1 Apr 2018

Gantner Pierre, Lee Guinevere Q, Rey David, Mesplede Thibault, Partisani Marialuisa, Cheneau Christine, Beck-Wirth Geneviève, Faller Jean-Pierre, Mohseni-Zadeh Mahsa, Martinot Martin, Wainberg Mark A, Fafi-Kremer Samira

Abstract excerpt

Objectives: Better understanding of the dynamics of HIV reservoirs under ART is a critical step to achieve a functional HIV cure. Our objective was to assess the genetic diversity of archived HIV-1 DNA over 48 weeks in blood cells of individuals starting treatment with a dolutegravir-based regimen. Methods: Eighty blood samples were prospectively and longitudinally collected from 20 individuals (NCT02557997)...

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Identifiers

PMID: 29244129
DOI: 10.1093/jac/dkx475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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