Article
Chemokine (C-C Motif) Receptor-Like 2 is not essential for lung injury, lung inflammation, or airway hyperresponsiveness induced by acute exposure to ozone.
Physiological reports - 1 Dec 2017
Malik Farhan, Cromar Kevin R, Atkins Constance L, Price Roger E, Jackson William T, Siddiqui Saad R, Spencer Chantal Y, Mitchell Nicholas C, Haque Ikram U, Johnston Richard A
Abstract excerpt
Inhalation of ozone (O3), a gaseous air pollutant, causes lung injury, lung inflammation, and airway hyperresponsiveness. Macrophages, mast cells, and neutrophils contribute to one or more of these sequelae induced by O3 Furthermore, each of these aforementioned cells express chemokine (C-C motif) receptor-like 2 (Ccrl2), an atypical chemokine receptor that facilitates leukocyte chemotaxis. Given that Ccrl2 is...
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