Article
Ozone-Induced Type 2 Immunity in Nasal Airways. Development and Lymphoid Cell Dependence in Mice.
American journal of respiratory cell and molecular biology - 1 Mar 2016
Ong Chee Bing, Kumagai Kazuyoshi, Brooks Phillip T, Brandenberger Christina, Lewandowski Ryan P, Jackson-Humbles Daven N, Nault Rance, Zacharewski Timothy R, Wagner James G, Harkema Jack R
Abstract excerpt
Inhalation exposures to ozone commonly encountered in photochemical smog cause airway injury and inflammation. Elevated ambient ozone concentrations have been epidemiologically associated with nasal airway activation of neutrophils and eosinophils. In the present study, we elucidated the temporal onset and lymphoid cell dependency of eosinophilic rhinitis and associated epithelial changes in mice repeatedly...
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