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Article

Multidimensional Bone Density Phenotyping Reveals New Insights Into Genetic Regulation of the Pediatric Skeleton.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 May 2018

Mitchell Jonathan A, Chesi Alessandra, Cousminer Diana L, McCormack Shana E, Kalkwarf Heidi J, Lappe Joan M, Gilsanz Vicente, Oberfield Sharon E, Shepherd John A, Kelly Andrea, Zemel Babette S, Grant Struan Fa

Abstract excerpt

Osteoporosis is a complex disease with developmental origins. It is therefore important to understand the genetic contribution to pediatric areal bone mineral density (aBMD). Individual skeletal site phenotyping has been primarily used to identify pediatric aBMD loci. However, this approach is limited because there is a degree of aBMD discordance across skeletal sites. We therefore applied a novel...

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PMID: 29240982
DOI: 10.1002/jbmr.3362
PMCID: PMC7473448

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CPED1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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