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Article

Physical Activity Benefits the Skeleton of Children Genetically Predisposed to Lower Bone Density in Adulthood.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2016

Mitchell Jonathan A, Chesi Alessandra, Elci Okan, McCormack Shana E, Roy Sani M, Kalkwarf Heidi J, Lappe Joan M, Gilsanz Vicente, Oberfield Sharon E, Shepherd John A, Kelly Andrea, Grant Struan Fa, Zemel Babette S

Abstract excerpt

Both genetics and physical activity (PA) contribute to bone mineral density (BMD), but it is unknown if the benefits of physical activity on childhood bone accretion depend on genetic risk. We, therefore, aimed to determine if PA influenced the effect of bone fragility genetic variants on BMD in childhood. Our sample comprised US children of European ancestry enrolled in the Bone Mineral Density in Childhood...

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Identifiers

PMID: 27172274
DOI: 10.1002/jbmr.2872
PMCID: PMC4970901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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