Article
A trans-ethnic genome-wide association study identifies gender-specific loci influencing pediatric aBMD and BMC at the distal radius.
Human molecular genetics - 1 Sept 2015
Chesi Alessandra, Mitchell Jonathan A, Kalkwarf Heidi J, Bradfield Jonathan P, Lappe Joan M, McCormack Shana E, Gilsanz Vicente, Oberfield Sharon E, Hakonarson Hakon, Shepherd John A, Kelly Andrea, Zemel Babette S, Grant Struan F A
Abstract excerpt
Childhood fractures are common, with the forearm being the most common site. Genome-wide association studies (GWAS) have identified more than 60 loci associated with bone mineral density (BMD) in adults but less is known about genetic influences specific to bone in childhood. To identify novel genetic factors that influence pediatric bone strength at a common site for childhood fractures, we performed a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.