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Article

The Polygenic and Monogenic Basis of Paediatric Fractures.

Current osteoporosis reports - 1 Oct 2021

Ghatan S, Costantini A, Li R, De Bruin C, Appelman-Dijkstra N M, Winter E M, Oei L, Medina-Gomez Carolina

Abstract excerpt

PURPOSE OF REVIEW: Fractures are frequently encountered in paediatric practice. Although recurrent fractures in children usually unveil a monogenic syndrome, paediatric fracture risk could be shaped by the individual genetic background influencing the acquisition of bone mineral density, and therefore, the skeletal fragility as shown in adults. Here, we examine paediatric fractures from the perspective of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33945105
DOI: 10.1007/s11914-021-00680-0
PMCID: PMC8551106

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