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Bone morphogenetic protein receptors and signal transduction

17 Sept 2009

Abstract excerpt

Bone morphogenetic proteins (BMPs) exhibit broad spectra of biological activities in various tissues, including bone, cartilage, blood vessels, heart, kidney, neurons, liver and lung. BMPs are members of the transforming growth factor-beta (TGF-beta) family that bind to type II and type I serine-threonine kinase receptors, and transduce signals through Smad and non-Smad signalling pathways. Recent findings have...

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PMID: 19762341
DOI: 10.1093/jb/mvp148

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