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Bone morphogenetic proteins in development and progression of breast cancer and therapeutic potential (Review)

21 Sept 2009

Abstract excerpt

Bone morphogenetic proteins (BMPs) belong to the TGF-beta superfamily, which plays important roles in foetal and postnatal development and also maintains the homeostasis of various tissues and organs. Due to the critical role played by BMPs in bone formation and bone turnover, the implication of these molecules in bone metastasis has been intensively studied over the past decade. BMPs have been implicated in the...

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PMID: 19787192
DOI: 10.3892/ijmm_00000269

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