Article
The family of bone morphogenetic proteins.
Kidney international - 1 Jun 2000
Ducy P, Karsenty G
Abstract excerpt
The family of bone morphogenetic proteins. Bone morphogenetic proteins (BMPs) are secreted signaling molecules belonging to the transforming growth factor-beta (TGF-beta) superfamily of growth factors. The first BMPs were originally identified by their ability to induce ectopic bone formation when implanted under the skin of rodents. In this ectopic overexpression assay, there was a recapitulation of all the...
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