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Article

Tumor Necrosis Factor-producing T-regulatory Cells Are Associated With Severe Liver Injury in Patients With Acute Hepatitis A.

Gastroenterology - 1 Mar 2018

Choi Yoon Seok, Jung Min Kyung, Lee Jeewon, Choi Seong Jin, Choi Sung Hoon, Lee Hyun Woong, Lee Jong-Joo, Kim Hyung Joon, Ahn Sang Hoon, Lee Dong Hyeon, Kim Won, Park Su-Hyung, Huh Jun R, Kim Hyoung-Pyo, Park Jun Yong, Shin Eui-Cheol

Abstract excerpt

BACKGROUND AND AIMS: CD4+CD25+Foxp3+ T-regulatory (Treg) cells control immune responses and maintain immune homeostasis. However, under inflammatory conditions, Treg cells produce cytokines that promote inflammation. We investigated production of tumor necrosis factor (TNF) by Treg cells in patients with acute hepatitis A (AHA), and examined the characteristics of these cells and association with clinical...

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Identifiers

PMID: 29229400
DOI: 10.1053/j.gastro.2017.11.277
PMCID: PMC5847455

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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