Article
CD4+Foxp3+CD25+/- Tregs characterize liver tissue specimens of patients suffering from drug-induced autoimmune hepatitis: A clinical-pathological study.
Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Apr 2018
Qu Li-Mei, Wang Shu-Hua, Yang Kun, Brigstock David R, Sun Li, Gao Run-Ping
Abstract excerpt
BACKGROUND: The diagnosis of drug-induced autoimmune hepatitis (DIAIH) and its differentiation from idiopathic autoimmune hepatitis (AIH) is challenging. This study aimed to differentiate DIAIH from AIH by comparing the biochemical changes, histological features, and frequencies of CD4+Foxp3+CD25+/- regulatory T cells (Tregs) in liver tissues or peripheral blood lymphocytes. METHODS: A total of 15 DIAIH patients...
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