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Article

Phenotypic Changes of PD-1 and GITR in T Cells Are Associated With Hepatitis B Surface Antigen Seroclearance.

Journal of clinical gastroenterology - 1 Jan 2022

Liu Fen, Zhang Saisai, Wong Danny Ka-Ho, Huang Fung Yu, Cheung Ka-Shing, Mak Lung Yi, Fung James, Yuen Man-Fung, Seto Wai-Kay

Abstract excerpt

BACKGROUND: Regulatory T cells (Tregs) possess hepatitis B virus (HBV)-specific immunoregulatory effects in chronic HBV infection. The role of Tregs in spontaneous seroclearance of hepatitis B surface antigen (HBsAg) remains to be determined. METHODS: We recruited treatment-naive chronic HBV patients achieving spontaneous HBsAg seroclearance (experimental group) and matched HBsAg-positive controls. Peripheral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33122602
DOI: 10.1097/MCG.0000000000001461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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