[The phenotype and function of CD4+ CD25+ regulatory T cells in hepatitis B patients].

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Article

[The phenotype and function of CD4+ CD25+ regulatory T cells in hepatitis B patients].

Zhonghua nei ke za zhi - 1 Aug 2006

Fu Jun-liang, Xu Dong-ping, Shi Ming, Zhang Hui, Jin Lei, Tang Zi-rong, Wang Fu-sheng

Abstract excerpt

OBJECTIVE: Our aim was to investigate the frequency, phenotype and function of CD4+ CD25 high regulatory T cells (Treg) in patients with acute and chronic hepatitis B (AHB, CHB). METHODS: Peripheral blood mononuclear cells (PBMCs) from 16 AHB patients at acute phase (week 1 of illness), 72 CHB patients, and 32 health subjects were analyzed for Treg frequency and CD45RO, CD45RA, CD95 and HLA-DR phenotype by flow...

Topics

Antigens, CD
Antigens, Differentiation
CD4 Antigens
CTLA-4 Antigen
Case-Control Studies
Flow Cytometry
Forkhead Transcription Factors
Hepatitis B
Humans
Interleukin-2 Receptor alpha Subunit
Phenotype
RNA, Messenger
Reverse Transcriptase Polymerase Chain Reaction
T-Lymphocytes, Regulatory

Source

Open in PubMed

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PMID: 17074148

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