Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease.

Journal of translational medicine - 11 Dec 2017

Nuij V J A A, Peppelenbosch M P, van der Woude C J, Fuhler G M

Abstract excerpt

BACKGROUND: The role of single nucleotide polymorphisms (SNPs) associated with inflammatory bowel disease (IBD) is gaining interest. With the advent of novel therapies, personalized treatment in IBD is a future goal. We wondered whether IBD-associated SNPs are able to predict response to anti-TNFα treatment. METHODS: Data on treatment use and primary response, loss of response and side effects to anti-TNFα...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adalimumab
Share to Autophagy-Related Proteins
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Association Studies

Share to Inflammatory Bowel Diseases

Share to Logistic Models

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29228965
DOI: 10.1186/s12967-017-1355-9
PMCID: PMC5725822

Genes

CCR6
NCF4
NOD2
XBP1
IRGM
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease.PMID 29228965Read ↗

Genetic polymorphism in ATG16L1 gene influences the response to adalimumab in Crohn's disease patients.Semantic proximity Read ↗

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.Semantic proximity Read ↗

ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes.Semantic proximity Read ↗

Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach.Semantic proximity Read ↗

Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene.Semantic proximity Read ↗

Genetic Polymorphisms of NOD2 and ATG16L1 in Different Types of Digestive Tract Inflammation.Semantic proximity Read ↗

Role of ATG16L1 Thr300Ala polymorphism in inflammatory bowel disease: a Study in the Spanish population and a meta-analysis.Semantic proximity Read ↗

IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.Semantic proximity Read ↗

Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene.Semantic proximity Read ↗

Genetic variants involved in innate immunity modulate the risk of inflammatory bowel diseases in an understudied Malaysian population.Semantic proximity Read ↗

Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms.Semantic proximity Read ↗

Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.