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Article

Multiple common and rare variants of ABCG2 cause gout

1 Aug 2017

Abstract excerpt

Objective Previous studies have suggested an association between gout susceptibility and common dysfunctional variants in ATP-binding cassette transporter subfamily G member 2/breast cancer resistance protein (ABCG2/BCRP), including rs72552713 (Q126X) and rs2231142 (Q141K). However, the association of rare ABCG2 variants with gout is unknown. Therefore, we investigated the effects of rare ABCG2 variants on gout...

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PMID: 29225919
DOI: 10.1136/rmdopen-2017-000464

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