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Article

A meta-analysis of the associations between the Q141K and Q126X ABCG2 gene variants and gout risk.

International journal of clinical and experimental pathology - 1 Jan 2015

Li Rui, Miao Lei, Qin Liyan, Xiang Yang, Zhang Xiaojin, Peng Hui, Mailamuguli, Sun Yuping, Yao Hua

Abstract excerpt

BACKGROUND: Gout is an inflammatory disease in which genetic factors play a role. ABCG2 is a urate transporter, and the Q141K and Q126X variants of ABCG2 have been associated with a risk of developing gout, though previous studies of these associations have been inconsistent. Therefore, we conducted a meta-analysis to explore the relationship between these genetic variants and gout. METHODS: We examined 8...

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Identifiers

PMID: 26617691
PMCID: PMC4637776

Genes

ABCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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