Article
Genetic variation in the ABCG2 gene is associated with gout risk in the Chinese Han population.
Clinical rheumatology - 1 Jan 2016
Jiri Mutu, Zhang Le, Lan Bing, He Na, Feng Tian, Liu Kai, Jin Tianbo, Kang Longli
Abstract excerpt
Gout is a common type of arthritis that is characterized by hyperuricemia, tophi, and joint inflammation. Current evidence suggests that heredity contributes to the progression of gout. Previous studies have shown that regulation of the ATP-binding cassette subfamily G member 2 (ABCG2) pathways plays a role in gout occurrence. To investigate and validate potential genetic associations with the risk of gout, we...
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