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Article

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jun 2009

Woodward Owen M, Köttgen Anna, Coresh Josef, Boerwinkle Eric, Guggino William B, Köttgen Michael

Abstract excerpt

Genome-wide association studies (GWAS) have successfully identified common single nucleotide polymorphisms (SNPs) associated with a wide variety of complex diseases, but do not address gene function or establish causality of disease-associated SNPs. We recently used GWAS to identify SNPs in a genomic region on chromosome 4 that associate with serum urate levels and gout, a consequence of elevated urate levels....

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19506252
DOI: 10.1073/pnas.0901249106
PMCID: PMC2700910

Genes

ABCG2
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.PMID 19506252Read ↗

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Functional Characterization of Clinically-Relevant Rare Variants in ABCG2 Identified in a Gout and Hyperuricemia CohortSemantic proximity Read ↗

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