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Article

NRAP-1 Is a Presynaptically Released NMDA Receptor Auxiliary Protein that Modifies Synaptic Strength.

Neuron - 20 Dec 2017

Lei Ning, Mellem Jerry E, Brockie Penelope J, Madsen David M, Maricq Andres V

Abstract excerpt

NMDA receptors (NMDARs) are a subtype of postsynaptic ionotropic glutamate receptors that function as molecular coincidence detectors, have critical roles in models of learning, and are associated with a variety of neurological and psychiatric disorders. To date, no auxiliary proteins that modify NMDARs have been identified. Here, we report the identification of NRAP-1, an auxiliary protein in C. elegans that...

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Identifiers

PMID: 29224722
DOI: 10.1016/j.neuron.2017.11.019
PMCID: PMC8819664

Genes

NRAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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