Article
NMDA receptors mediate olfactory learning and memory in Drosophila.
Current biology : CB - 12 Apr 2005
Xia Shouzhen, Miyashita Tomoyuki, Fu Tsai-Feng, Lin Wei-Yong, Wu Chia-Lin, Pyzocha Lori, Lin Inn-Ray, Saitoe Minoru, Tully Tim, Chiang Ann-Shyn
Abstract excerpt
BACKGROUND: Molecular and electrophysiological properties of NMDARs suggest that they may be the Hebbian "coincidence detectors" hypothesized to underlie associative learning. Because of the nonspecificity of drugs that modulate NMDAR function or the relatively chronic genetic manipulations of various NMDAR subunits from mammalian studies, conclusive evidence for such an acute role for NMDARs in adult behavioral...
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