Article
GRLD-1 regulates cell-wide abundance of glutamate receptor through post-transcriptional regulation.
Nature neuroscience - 1 Dec 2010
Wang George J, Kang Lijun, Kim Julie E, Maro Géraldine S, Xu X Z Shawn, Shen Kang
Abstract excerpt
AMPA receptors mediate most of the fast postsynaptic response at glutamatergic synapses. The abundance of AMPA receptors in neurons and at postsynaptic membranes is tightly regulated. It has been suggested that changes in synaptic AMPA receptor levels are an important regulatory event in synaptic plasticity and learning and memory. Although the local, synapse-specific regulation of AMPA receptors has been...
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