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Article

SOL-1 is an auxiliary subunit that modulates the gating of GLR-1 glutamate receptors in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jan 2006

Zheng Yi, Brockie Penelope J, Mellem Jerry E, Madsen David M, Walker Craig S, Francis Michael M, Maricq Andres V

Abstract excerpt

Most rapid excitatory synaptic signaling in the brain is mediated by postsynaptic ionotropic glutamate receptors (iGluRs) that are gated open by the neurotransmitter glutamate. In Caenorhabditis elegans, sol-1 encodes a CUB-domain transmembrane protein that is required for currents that are mediated by the GLR-1 iGluR. Mutations in sol-1 do not affect GLR-1 expression, localization, membrane insertion, or...

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Identifiers

PMID: 16418277
DOI: 10.1073/pnas.0504612103
PMCID: PMC1347967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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