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Article

Extensive phenotyping of the orofacial and dental complex in Crouzon syndrome.

Archives of oral biology - 1 Feb 2018

Khominsky Alexander, Yong Robin, Ranjitkar Sarbin, Townsend Grant, Anderson Peter J

Abstract excerpt

OBJECTIVES: Fibroblast growth factor receptor 2 (FGFR2) C342Y/+ mutation is a known cause of Crouzon syndrome that is characterised by craniosynostosis and midfacial hypoplasia. Our aim was to conduct extensive phenotyping of the maxillary, mandibular and dental morphology associated with this mutation. MATERIALS AND METHODS: Morphometric data were obtained from 40 mice, representing two genotypes (Crouzon and...

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Source

Identifiers

PMID: 29223639
DOI: 10.1016/j.archoralbio.2017.10.022

Genes

FGFR2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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